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REVERSAL OF DRUG RESISTANCE THROUGH OLIGONUCLEOTIDE COMPLEMENTARY TO PLASMODIUM FALCIPARUM SPECIFIC REGION
REVERSAL OF DRUG RESISTANCE THROUGH OLIGONUCLEOTIDE COMPLEMENTARY TO PLASMODIUM FALCIPARUM SPECIFIC REGION
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机译:通过恶性疟原虫特定区域补充的寡核苷酸逆转药物耐药性
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摘要
The present invention provides methods of resensitizing an anti-drug-resistant infectious agent to a drug. Also disclosed are synthetic oligonucleotides having a nucleotide sequence complementary to a region of pfmdr1 nucleic acid, and methods of down-regulating the expression of pfmdr nucleic acid using such oligonucleotides.
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