首页> 外国专利> REVERSAL OF DRUG RESISTANCE THROUGH OLIGONUCLEOTIDE COMPLEMENTARY TO PLASMODIUM FALCIPARUM SPECIFIC REGION

REVERSAL OF DRUG RESISTANCE THROUGH OLIGONUCLEOTIDE COMPLEMENTARY TO PLASMODIUM FALCIPARUM SPECIFIC REGION

机译:通过恶性疟原虫特定区域补充的寡核苷酸逆转药物耐药性

摘要

The present invention provides methods of resensitizing an anti-drug-resistant infectious agent to a drug. Also disclosed are synthetic oligonucleotides having a nucleotide sequence complementary to a region of pfmdr1 nucleic acid, and methods of down-regulating the expression of pfmdr nucleic acid using such oligonucleotides.
机译:本发明提供使抗药性感染剂对药物重新敏化的方法。还公开了具有与pfmdr1核酸的区域互补的核苷酸序列的合成寡核苷酸,以及使用此类寡核苷酸下调pfmdr核酸表达的方法。

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