Hidronaf compounds 4,5 - Di - 1,2-c isoxasoles, derivatives and Pharmaceutical compositions, Preparation methodSubstance Use as farmaceuticamenteactiva and uses for the manufacture of Medicines for the treatment of Psychiatric Disorders, anxiety, nausea, vomiting, Drug Dependence

摘要

In formula compound (I), a is hydrogen, hydrogen Xi, R1 is hydrogen, a group of 1-6 carbon tar, which is finally replaced by hydrogen Xi, alcoxi or ammonia water; arilo or heteromorphic, which is finally replaced by nitrogen, hydrogen Xi or alcoxi; or halogen, hydrogen Xi or alcoxi benzene; N is an integer of 1 or 2;Z is n, ch or C (CH);M is an integer from 1 to 3,X is hydrogen, hydrogen Xi, or alcoxi, and, where applicable, a drug salt, its geometric or optical isomer, or racemic mixture, which can be converted. Formula compound (I) seobtiene also describes the use of these compounds through formula response protocol (II): drugs used to treat anxiety, mental disorder, nausea, vomiting and drug dependence.