Reagents, kit, radio-labeled ltb4 binding agent, method for detecting sites of infection and inflammation in a mammal, method for imaging sites of infection and inflammation in a mammal, method for diagnosing disease in a mammal associated with minfection and inflammation, compounds and method of treating disease in a mammal associated with infection and inflammation

摘要

B "REAGENTS, KIT, RADIOR LABELED LTB4 CONNECTION AGENT, METHOD FOR DETECTING PLACES OF INFECTION AND INFLAMMATION IN A MAMMALIAN, METHOD FOR FORMING THE IMAGE OF INFECTION AND INFLAMMATION PLACES IN A MAMMALIAN, MULTIPLE OF A PHILOSOPHY IN A MULTIPLE HOMEMOMER, A PHOTOGRAPHY IN A MOMENT, IN A MULTIPLE MULTIPLE. ASSOCIATED WITH INFECTION AND INFLAMMATION, COMPOUNDS AND METHOD OF TREATING DISEASE IN A MAMMALIAN ASSOCIATED WITH INFECTION AND INFLAMMATION ". D The present invention presents new radiopharmaceutical products useful for the diagnosis of infection and inflammation, reagents and kits useful for the preparation radiopharmaceutical products, methods of imaging sites of infection and / or inflammation in a patient, and methods for diagnosing diseases associated with infection or inflammation in patients who need this diagnosis. Radiopharmaceuticals bind in vivo to the leukotriene B4 receptor (LTB4) on the surface of leukocytes, which accumulate at the site of infection and inflammation. The reagents obtained by the present invention are also useful for the treatment of diseases associated with infection and inflammation.