PROCESS FOR PREPARING 3/2 HYDRATE OF 7-/(7-(S)-AMINO-5-AZASPIRO/2.4/HEPTAN-5-YL/-8-CHLORO-6-FLUORO-1-/(1R,2S)- 2-FLUOROCYCLOPROPYL/-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID,

摘要

3/2 7 - [(7- (S) -Amino-5-azaspiro) 2.4 / heptan-5-yl] -8-chloro-6-fluoro-1- (1R, 2S) -2-fluorocyclopropane hydrate and anhydratepolyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acids, methods for the selective production of 3/2 hydrate, its crystals and antibacterial agents based thereon. 3/2 hydrate is obtained by treating crude 7 - [(7- (S) -amino-5-azaspirole][2,4 / heptan-5-yl] -8-chloro-6-fluoro-1 - [(1R, 2S) -2-fluorocyclopropyl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid in aqueous solvent or water or recrystallizing it from an aqueous solvent or water.ŕ