Coup-tfi directed therapies in the treatment of disease

摘要

Methods for the treatment of neurological diseases, bone disease, and hearing and balance diseases are provided. These comprise the step of administering an antagonist to COUP-TFI in a therapeutic effective amount. The antagonist to COUP-TFI can be used to also prevent degeneration of bone, and nerves and neurons. Additionally, a method includes the introduction of the COUP-TFI gene into the mammal wherein said introduced gene can be induced by an agonistic to COUP-TFI to enhance the growth of nerve tissue, bone tissue and inner ear tissue.