首页>
外国专利>
Process for screening substances having a modulating effect on an interleukin-5 receptor mediated cellular signal transmission pathway
Process for screening substances having a modulating effect on an interleukin-5 receptor mediated cellular signal transmission pathway
展开▼
机译:筛选对白介素5受体介导的细胞信号传递途径有调节作用的物质的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
A process is disclosed for screening substances having a modulating effect on the interleukine-5-receptor-dependent signal tranmission path in mammal cells. Test substances are applied on cells which express the functional interleukine-5-receptor and are transformed with a recombinant DNA containing a reporter gene and a regulatory sequence functionally linked thereto which is sensitive to a change in concentration of a secondary messenger substance of the interleukine-5- receptor-dependent signal transmission path. Substances specific to the interleukine-5- receptor-dependent signal transmission path and with potential pharmacological effect may be identified by this process.
展开▼