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Compound amino acid carboxilixo - 2 - 3 - 4 - ilo alcoxiisoxazol replaced that understands, Pharmaceutical Composition and Use thereof.
Compound amino acid carboxilixo - 2 - 3 - 4 - ilo alcoxiisoxazol replaced that understands, Pharmaceutical Composition and Use thereof.
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机译:理解的复方氨基酸羧苄索-2--3-4-伊洛昔康唑,药物组合物及其用途。
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摘要
1. 2-amine carboxylic acid derivatives substituted by (3-alcoxiisoxazol-4-il o) or sulfur analogues with general formula I or II, wherein R1 is optional alternative hydrogen, tar, acyl chloride, asphalt, cyclododecane (EN) ILO, ciloal-a LQ (EN / in) il Alq (EN / in) ILO or fenil Alq (EN / in); A is a hydrogen fuel coupling or spacing group; B is a CRA (nrrc) - cour5 group, wherein ra-rc is an independent hydrogen or tar, R5 is an opiva oximetry; or B is a third preparation group, wherein R2, R3 and R4 are independently selected from polyhydrogen and non aromatic hydrocarbons.Phenyl and goblin pitch are linked to a group of isomerized substances, or R3 and R4, to form pitch, acrylonitrile or pitch, or R4 and R2 are related to each other to form an optional group of sulphurous acid or pitch, or ch2-o-ch2; E is cour6, where R6 is defined as R5, or E is R5. Tetracarboxylic acid or tricarboxylic acid; X is o or s; E is o or s; they are excitatory amino acids (EAA),In particular, amperometric and / or NMDA receptor ligation is a tool for the treatment of cerebral ischemia, dehuntington's disease, aseptic epilepsy, Parkinson's disease, Alzheimer's disease, schizophrenia, pain, depression and anxiety. It also provides a pharmaceutical ingredient that includes them and uses it to make a pharmaceutical synthesis.
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