DERIVATIVES OF 1,4-DIAZABICYCLO2.2.2OCT-2-YLMETHYLBENZOATE, METHOD FOR THEIR PREPARATION AND APPLICATION IN THERAPY

摘要

The compounds are ligands of the serotoninergetic receptors of the types 5-HT3 and/or 5-HT4 and act as 5-HT4 agonists and/or 5-HT5 antagonists. The have the general formula where R1 means methyl group, X1 means hydrogen atom or OR1 and X1 together form a group with the formula -O(CH2)2-, -O(CH2)3-, O(CH2)20- or -O(CH2)30-; X2 is hydrogen atom or aminogroup, and X3 is halogen atom. 4 claims