Pharmaceutical process and compositions for lowering the level of uric acid in the human body and for prophylaxis of gout, hyperuricemia or coronary heart disease in humans, and use of a compound

摘要

"PHARMACEUTICAL PROCESSES AND COMPOSITIONS FOR LOWERING THE LEVEL OF URIC ACID IN THE HUMAN ORGANISM AND FOR DROP PROPHYLAXIS, HYPERURICEMIA OR CORONARY HEART DISEASE IN HUMANS, AND, USE OF A COMPOUND". A compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein R ~ 1 ~ and R ~ 2 ~ are independently H or methyl (for example, N, N-dimethyl-1- [1- (4- chlorophenyl) cyclobutyl] -3-mentylbutyl amine, optionally in the form of its monohydrate) is used to lower the level of uric acid in humans, for example, in humans suffering from or at risk of developing gout, hyperuricemia or coronary heart disease.