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Compositions for the treatment and Prevention of the use of uninhibidor arterial Thrombosis and factor Xa alone or in combination with Antiplatelet drugs

机译:单独或与抗血小板药物联合使用的用于治疗和预防无抑制剂动脉血栓形成和Xa因子的组合物

摘要

1. The drug compounds with the characteristics of direct or indirect selective strong inhibitor of XA factor, combined with one or more platelet anticoagulant active compounds and possibly one or more drug acceptable vehicles, can perform the antiretroviral effect through the anti hematopoietin III. Pharmaceutical ingredients according to claim 1characterized in that they comprise an Iib / IIIa glycoprotein antagonist as platelet antiaggregant and methyl O- (2-deoxy-2-sulfoamino-6-O-sulfo-aD-glucopyranosyl) - (1-4) -O- (acid- β-D-glucopyranosyluronic) - (1-4) -O- (2-deoxy-2-sulfoamino-3,6-di-O-sulfo - aD-glucopyranosyl- (1-4) -O- (acid 2 -O-sulfo-aL-idopyranosyluronic) - (1-4) -deoxy-2-sulfoamino-6-O-sulfo-aD-glucopira-noside whose anion possesses structure (B) or one of its pharmaceutically acceptable salts, as an indirect selective factor Xa inhibitor.
机译:1.具有直接或间接选择性XA因子强抑制剂特性的药物化合物,与一种或多种血小板抗凝活性化合物以及可能的一种或多种药物可接受的载体结合,可以通过抗血细胞生成素III发挥抗逆转录病毒作用。 2.根据权利要求1的药物成分,其特征在于它们包含作为血小板抗凝剂的IIb / IIIa糖蛋白拮抗剂和甲基O-(2-脱氧-2-磺氨基-6-O-磺基-aD-吡喃葡萄糖基)-(1-4)-O -(酸-β-D-吡喃葡萄糖基糖醛酸)-(1-4)-O-(2-脱氧-2-磺胺基-3,6-二-O-磺基-aD-吡喃葡萄糖基-(1-4)-O- (酸2 -O-磺基-aL-氨基吡喃糖基糖醛酸)-(1-4)-阴离子具有结构(B)的脱氧-2-磺胺基-6-O-磺基-aD-葡萄糖基吡喃糖苷或其药学上可接受的盐之一,作为间接选择因子Xa抑制剂。

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