首页> 外国专利> COMPOUNDS CONTAINING A MICHAEL-ACCEPTOR, ESPECIALLY MALEIMIDE OR MALEIC ACID DERIVATIVES, DIRECTLY OR INDIRECTLY LINKED TO A CHROMOPHORE AND THEIR USE IN LONG LASTING SUNSCREEN COMPOSITIONS

COMPOUNDS CONTAINING A MICHAEL-ACCEPTOR, ESPECIALLY MALEIMIDE OR MALEIC ACID DERIVATIVES, DIRECTLY OR INDIRECTLY LINKED TO A CHROMOPHORE AND THEIR USE IN LONG LASTING SUNSCREEN COMPOSITIONS

机译:包含迈克尔受体的化合物,尤其是马来酰亚胺或马来酸衍生物,直接或间接地与色度连接,并在长效防晒组合物中使用

摘要

The present invention relates to compounds which are useful as sunscreens. The compounds persist on the skin for much longer than conventional sunscreens because they comprise a Michael acceptor linked directly or indirectly to a chromophore. The Michael acceptor is capable of undergoing a conjugate addition reaction with thiol groups present in cysteine residues of keratin and thus the compound is chemically bound to the skin and will not be removed by immersion in water.
机译:本发明涉及用作防晒剂的化合物。该化合物比常规防晒霜在皮肤上的保留时间更长,因为它们包含直接或间接与发色团连接的迈克尔受体。迈克尔受体能够与角蛋白的半胱氨酸残基中存在的硫醇基团进行共轭加成反应,因此该化合物化学结合到皮肤上并且不会通过浸入水中而除去。

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