COUMARIN-BASED OR MELILOT-BASED TRANSDERMAL PLASTERS

摘要

Transdermal plaster containing melilot or coumarin as the active ingredient, comprising: a) an impermeable substrate layer; b) an adhesive layer containing the active principle dispersed therein and containing as the adhesive polymer an acrylic polymer selected from the group consisting of: (I) a mixture of: the cationic copolymer (b-1) dimethylamino-ethyl-methacrylate / neutral ester of methacrylic acid with one or more C1-C10 alcohols, the neutral copolymer (b-1-(i)) ethyl acrylate / methyl methacrylate, or else (II) an anionic copolymer (b-1(ii)) methacrylic acid / methyl methacrylate, said adhesive layer (b) moreover comprising the following components: b-2) glycerine, b-3) polyethylene glycol 400; c) a protective film which may be removed just before use.