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A method for preparation of oil-in-water type cosmetic containing retinoids having improved stability

机译:一种具有改善的稳定性的含有类维生素A的水包油型化妆品的制备方法

摘要

PURPOSE: A manufacturing process for hydrophilic cosmetic material containing stability-improved retinoid is provided, which maintains 82% of retinoid after storing the hydrophilic cosmetic material for 4weeks at 45deg.C. CONSTITUTION: The manufacturing process for hydrophilic cosmetic material containing stability-improved retinoid comprises the steps of: (1) mixing surfactant showing phase-reverse temperature at 45deg.C 0.5-20wt.%, fatty alcohol 0.1-10wt.% and cholesterol 0.1-10wt.%, adding distilled water at 70deg.C, mixing to emulsify, and adding retinoid as inner phase, cooling to room temperature to get SWLC(Super Wide Liquid Crystal) base of 3,000-50,000nm size; (2) emulsifying by adding surfactant for forming liquid-crystal to water phase, cooling to room temperature, and adding water-soluble polymer to get gel-type base; and (3) mixing the SWLC base of (1) to the gel-type base of (2) to get the hydrophilic cosmetic material.
机译:用途:提供了一种包含稳定性得到改善的类维生素A的亲水性化妆品材料的制造工艺,该方法在将亲水性化妆品材料在45°C下保存4周后,可维持82%的类维生素A。组成:包含稳定性得到改善的类维生素A的亲水化妆品的制造工艺包括以下步骤:(1)混合在45°C下显示相变温度的表面活性剂0.5-20wt。%,脂肪醇0.1-10wt。%和胆固醇0.1- 10wt。%,在70℃下加入蒸馏水,混合乳化,并加入类维生素A作为内相,冷却至室温,得到3,000-50,000nm尺寸的SWLC(超宽液晶)基底; (2)通过在水相中加入用于形成液晶的表面活性剂进行乳化,冷却至室温,并加入水溶性聚合物得到凝胶型碱。 (3)将(1)的SWLC基质与(2)的凝胶型基质混合,得到亲水性化妆品。

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