首页> 外国专利> PHARMACEUTICAL COMPOSITION FOR RECOVERY FUNCTION OF SYMPATHETIC-ADRENAL SYSTEM, METHOD OF EVALUATION OF INDIVIDUAL EFFECTIVENESS OF THIS COMPOSITION FOR PATIENT THERAPY

PHARMACEUTICAL COMPOSITION FOR RECOVERY FUNCTION OF SYMPATHETIC-ADRENAL SYSTEM, METHOD OF EVALUATION OF INDIVIDUAL EFFECTIVENESS OF THIS COMPOSITION FOR PATIENT THERAPY

机译:交感神经-肾上腺系统恢复功能的药物组合物,该组合物对患者治疗的个体疗效评估方法

摘要

FIELD: medicine, biochemical pharmacology. SUBSTANCE: invention relates to the developed pharmaceutical composition based on dopamine-generating substance, in part, dihydroxyphenyl-alanine. This substance is a dopamine precursor and it is taken in composition in the amount 2.5; 4.5; 20.0; 50.0 or 90.0 mg/1000 mg of accessory substances, for example, starch, sucrose, lactose and so on and sunflower, peanut oil, cod fish liver and others also. Also, composition has additionally antioxidant taken in the amount 4.0-20.0 mg and glucocortico-steroid taken in the amount 0.01-10.0 mg. Invention involves also method of evaluation of individual effectiveness of the composition. This method is developed on the basis of adrenographic method of examination. Method involves realization of functional test by administration in patient one-half, one- or two-fold dose of composition with maximal dose of dopamine-generating substance. EFFECT: broadened arsenal of agents for control of disorders of sympathetic-adrenal system of body. 9 cl, 6 ex
机译:领域:医学,生化药理学。物质:本发明涉及基于产生多巴胺的物质,部分地为二羟基苯基丙氨酸的已开发的药物组合物。该物质是多巴胺前体,其组成量为2.5; 4.5; 20.0; 50.0或90.0 mg / 1000 mg辅助物质,例如淀粉,蔗糖,乳糖等,以及向日葵,花生油,鳕鱼肝等。另外,组合物还具有4.0-20.0mg的抗氧化剂和0.01-10.0mg的糖皮质激素。本发明还涉及评估组合物的个体有效性的方法。该方法是在肾上腺检查的基础上发展起来的。该方法涉及通过向患者施用最大剂量多巴胺生成物质的一半,一倍或两倍剂量的组合物来实现功能测试。功效:扩大了用于控制人体交感肾上腺系统疾病的药物库。 9 cl,6 ex

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