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Expression of bacterial potassium channels in eukaryotic host cells and their use for the identification of antibiotics

机译:细菌钾通道在真核宿主细胞中的表达及其在抗生素鉴定中的应用

摘要

The subject matter of the invention are eukaryotic expression vectors, the expression of bacterial potassium channels enable the lct b family. Furthermore, according to the invention, these vectors containing enclosed host cells which express the bacterial potassium channels. Furthermore, the first time, a method for identifying substances is made available, the bacterial potassium channels opening, closing, modulating, can activate or deactivate and, thus, bactericides or bacteriostatic properties. According to a particular embodiment of the invention, the method for identifying or finding of antibiotics.
机译:本发明的主题是真核表达载体,细菌钾通道的表达使lct b家族成为可能。此外,根据本发明,这些载体包含表达细菌钾通道的封闭宿主细胞。此外,首次提供了一种用于鉴定物质的方法,细菌钾通道的打开,关闭,调节,可以激活或失活,因此具有杀菌剂或抑菌特性。根据本发明的特定实施方案,用于鉴定或发现抗生素的方法。

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