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Methods and compositions for modulating nuclear trafficking of proteins
Methods and compositions for modulating nuclear trafficking of proteins
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机译:调节蛋白质核转运的方法和组合物
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摘要
Methods are provided to regulate the trafficking of nuclear proteins, including the high molecular weight forms of FGF-2, to the nucleus. A nuclear trafficking component, which is approximately 29 kD, is identified as binding to and regulating nuclear localization of FGF-2. Inhibitors of the binding of the 29 kD component and FGF-2 are provided.
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