首页> 外国专利> Salt guanosine isopropyl Methyl 2 - (3 - N - propoxifenoxi) ethyl amine, Process for their preparation, Pharmaceutical composition containing them and their use in the treatment of pain.

Salt guanosine isopropyl Methyl 2 - (3 - N - propoxifenoxi) ethyl amine, Process for their preparation, Pharmaceutical composition containing them and their use in the treatment of pain.

机译:盐鸟嘌呤异丙基甲基2-(3- [N-丙氧新诺西)乙基]胺,其制备方法,包含它们的药物组合物及其在疼痛治疗中的用途。

摘要

Isopropyl methyl [2 - (3-n-propoxy) ethyl] amine, methylphosphate; process for manufacturing such isopropyl methyl [2 - (3-n-propoxy) ethyl] amine, pharmaceutical formulation containing the substance and its use in medicine. Laiso propil met - [2 - (3-n-propoxiphenxi) ethi] amine is an anesthetic force majeure; it is used as an anesthetic for pain treatment,Even local pain 2 - [2 - (3-n-propoxifen oxy) ethyl] amine can be used to introduce the crystallization intermediate into the preparation process of isopropyl methyl [2 - (3-n-propoxifenxi) ethyl] amine. This adds a simple and convenient step in a reaction process where all the other intermediaries are syrup. Such wordsIt avoids distillation of processes that used to take a lot of time and effort. 1. Isopropyl methyl polyphosphate [2 - (3-n-hydroxy) ethyl] ammonia water was separated from an intermediate with high purity, which can be converted into corresponding isopropyl methyl - [2 - (3-n-propoxiphenxi) ethyl] ammonia water at the same time, through simple sliding.
机译:异丙基甲基[2-(3-正丙氧基)乙基]胺,磷酸甲酯;异丙基甲基[2-(3-正丙氧基)乙基]胺的制备方法,含有该物质的药物制剂及其在医学中的用途。 Laiso propil met-[2-(3-n-propoxiphenxi)ethi]胺是麻醉药不可抗药;它用作疼痛治疗的麻醉剂,甚至局部疼痛2-[2-(3-正丙氧芬氧基)乙基]胺也可用于将结晶中间体引入异丙基甲基[2-(3-正丙氧芬西乙]胺。这在所有其他中间物都是糖浆的反应过程中增加了一个简单方便的步骤。这样的话避免了过去费时费力的过程的提炼。 1.从高纯度的中间体中分离出异丙基甲基多磷酸[2-(3-(n-羟基)乙基]氨]水,该中间体可以转化为相应的异丙基甲基-[[2-(3-n-丙氧苯基]乙基]氨]通过简单的滑动同时注水。

著录项

  • 公开/公告号AR017199A1

    专利类型

  • 公开/公告日2001-08-22

    原文格式PDF

  • 申请/专利权人 ASTRAZENECA AB;

    申请/专利号AR1998P106241

  • 发明设计人

    申请日1998-12-09

  • 分类号C07C217/20;A61K31/135;

  • 国家 AR

  • 入库时间 2022-08-22 01:26:17

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