Process for producing bacteria corineformes having improved productivity of amino acid or nucleic acid synthesizing genes, glutamic acid and arginine synthetase.Bacteria corineformes producing glutamic acid, and arginine, and producing, processes to produce an amino acid or nucleic acid by fermentation.And for producing L-glutamic acid by fermentation.

摘要

PROCEDURE FOR BACTORY PRODUCERS BEING IMPROVED PRODUCTIVENESS OF NUCLEAN ENVIRONMENT OR ACID GENES SINTIATING GLUTMIC ACID, AND ARGININ SYNTHESIS, CORINEFORM BACTERIES PRODUCING GLUT E ACITY, AND ARGIN PRODUCING, AND PROCEDURES FOR PRODUCING AN AMOUNT OR A PRODUCTION IN ARCHIC L-GLUTEMIC ACID BY FERTIATION." A process to produce corineform bacteria having improved amino acid or nucleic acid productivity comprises the steps to introduce a mutation into a sequence of bio-synthesizing gene promoter amino acid or acidnucleic in a chromosome of a corineform bacterium to make it closer to a consensus session or to introduce a change in a biosynthesis gene promoter's secretion by amino acid or nucleic acid in a chromosome of a corineform bacterium by recombination of genesto bring it closer to a consensus sequence, to obtain microorganism mutants producing amino acid or corineform nucleic acid, cultivate mutants and select a mutant capable of producing the amino acid or nucleic acid desired in a large amount. This process can build a mutant capable of properly enriching or controlling the expression of an intended gene without using a plasmid and also capable of producing amino acids in a high yield by recombination or mutation.