Process to treat or reduce the risk of acquiring a condition selected from the group consisting of atherosclerosis, endometrial cancer, uterine cancer, ovarian cancer, lack of vaginal lubrication, and loss of muscle mass, pharmaceutical composition, and, kit.

摘要

PROCESS TO TREAT OR REDUCE THE RISK OF ACQUIRING A SELECTED CONDITION FROM THE GROUP CONSISTING OF AEROSCLEROSIS, ENDOMETRIAL CANCER, UTERINE CANCER, OVARIAN CANCER, LACK OF VAGINAL LUBRICATION, AND LOSS OF MACHINE, MASSAGE, MASSAGE medical treatment and / or inhibition of the development of osteoporosis, breast cancer, hypercholesterolemia, hyperlipidemia, or atherosclerosis in susceptible warm-blooded animals, including humans, involving the administration of selective estrogen modulator and receptor, particularly compounds having the general structure (I ) and a quantity of sexual steroid precursor selected from the group consisting of dehydroepiandrosterone, dehydroepiandrosterone sulfate, androst-5-eno- 3 225, 17 225 -diol and compounds converted in vivo to one of the following precursors. administration of bisphosphonates in combination with selective estrogen receptor modulators and / or sexual steroid precursor is described for medical treatment and / or inhibiting the development of osteoporosis. Pharmaceutical compositions for releasing active ingredient (s) and kit (s) usable in the invention are also described.