Compound, processes for the production of a compound and for the conversion of a crystalline form to a compound, pharmaceutical formulation, use of a compound, and, process for treating a condition where thrombin inhibition is required or desired

摘要

"COMPOUND, PROCESSES FOR THE PRODUCTION OF A COMPOUND AND FOR THE CONVERSION OF A CRYSTALLINE FORM OF A COMPOUND, PHARMACEUTICAL FORMULATION, USE OF A COMPOUND, AND, PROCESS FOR TREATING A CONDITION WHERE THE THROMBINE INHIBITION IS REQUIRED" OR DESIRED " EtO ~ 2 ~ C-CH ~ 2 ~ - (R) Cgl-Aze-Pab-OH, or a pharmaceutically acceptable salt thereof, in a form that is substantially crystalline. It has been observed that the crystalline forms of EtO ~ 2 ~ C-CH ~ 2 ~ - (R) Cgl-Aze-Pab-OH have a high chemical and solid stability, compared to the amorphous forms of the compound.