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Pharmaceutical composition for the treatment of acute pain by sublingual administration, use of fentanyl or a pharmaceutically acceptable salt thereof, and process for the treatment of acute pain
Pharmaceutical composition for the treatment of acute pain by sublingual administration, use of fentanyl or a pharmaceutically acceptable salt thereof, and process for the treatment of acute pain
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机译:通过舌下给药治疗急性疼痛的药物组合物,芬太尼或其药学上可接受的盐的用途以及治疗急性疼痛的方法
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摘要
"PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF ACUTE PAIN BY SUBLINGUAL ADMINISTRATION, USE OF FENTANILLA OR A PHARMACEUTICALLY ACCEPTABLE SALT OF THE SAME, AND PROCESS FOR THE TREATMENT OF ACUTE PAIN" A pharmaceutical composition for the treatment of acute pain by sublingual administration is described. The composition comprises an ordered mixture, essentially free of water, fentanyl or a pharmaceutically acceptable salt thereof, in the form of micro particles which are adhered to the surface of the carrier particles which are substantially larger than the fentanyl particles, and are essentially soluble in water in water. In a preferred embodiment, the composition also contains a bioadhesion and / or mucoadhesion promoting agent. The invention also relates to the preparation of the composition, and the use of the composition for the treatment of acute pain.
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