Clinical use of thiazolidinediones alone or in conjunction with other agents to block oxytocin-mediated actions, such as uterine contractions in premature birth or lactation

摘要

Patent of Invention: "CLINICAL USE OF THIAZOLIDINADIONASOZINHAS OR IN CONJUNCTION WITH OTHER AGENTS TO CONCLUDE THE MEASURES MEASURED BY Oxytocin, TALCOMING UTERINE CONTRACTIONS IN PREMATURE OULACATION CHART". The present invention provides methods of preventing or reducing the action mediated by oxytocin using a thiazolidinedione, such as troglitazone, or tipothiazolidinedione compounds. These methods describe the use of these compounds alone or in combination with at least one other agent, such as a tocolytic agent. This offers a new therapeutic regimen for the treatment of actions mediated by oxytocin, for example induction of uterine contractions, release of prostagiandin, and weakening of milk. Therefore, conditions such as preterm delivery and delivery before Cesarean delivery can be treated by these methods.