DNA construct, affecting expression of endogenous IFNA2 gene, isolated nucleic acid, homologous recombinant mammal cell, method of influencing expression of endogenous IFNA2 gene, method of administering the IFNA2 to an animal and production process of IFNA2

摘要

An isolated nucleic acid molecule that hybridizes under stringent conditions, or shares at least 80 % sequence identity, with a defined genomic region upstream of the coding region of the IFNA2 gene, and a DNA construct containing that DNA molecule as a targeting sequence for homologous recombination.