Wulin derivatives as antibacterial agents

摘要

It refers to that in a formula, R is h, tar, R1 is h, C = x-r9, X is s, O, N10, R10 is h, tar, n (+) (r ` 1o) 2, R'10 is tar, with appropriate anion, R9 is amino, tar, arilo, isopropene, mercato, if x is O, R9 is extra frontal h, R2 is arileno, isopropene, R4 and R5 are h, lo, R3 is R3.R6, R7 and R8 are h, deuterium; R and R2 form non aromatic heterocycles with N; R1 es-c (= x) - R9. The most popular compounds include: 14-o - (3-amino) phenyl-fluthrin-mutilin; 14-o - (3-amino) phenyl-fluthrin-2,4-tricyclohydroethane-mutilin, 14-o - (3-piperidin-2-il-carbonilamino) phenyl fluthrin, etc. It also refers to a preparation procedure and intermediate compounds. 1. Fungicide is an antibacterial agent, which can be used to treat bacterial and microbial infections, including strains resistant to penicillin, vancomycin and methicillin