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PHARMACEUTICAL AGENTS CONTAINING METALLIC COMPLEXOD CONTAINING PERFLUORALQUILO AND ITS USE IN TUMOR THERAPY AND INTERVENTIONAL RADIOLOGY

机译:含全氟喹啉类金属络合物的药物及其在肿瘤治疗和介入放射学中的应用

摘要

The invention relates to pharmaceutical agents containing perfluoroalkylated metal complexes of the general formula (I) RF-L-A and the use thereof in tumour therapy and interventional radiology, in which formula RF is a perfluorinated, straight-chain or branched carbon chain with the formula -CnF2nX, in which X is a terminal fluorine, chlorine, bromine, iodine or hydrogen atom and n represents the numbers 4-30, L is a binding group, and A is a metal complex or the salts thereof of organic and/or inorganic bases or amino acids or amino acid amides. L and A are defined in detail in the description.
机译:本发明涉及含有通式(I)RF-LA的全氟烷基化金属配合物的药物及其在肿瘤治疗和介入放射学中的用途,其中式RF是具有下式的全氟,直链或支链碳链: CnF2nX,其中X为末端氟,氯,溴,碘或氢原子,n表示4-30,L为键合基团,A为有机和/或无机碱的金属配合物或其盐或氨基酸或氨基酸酰胺。 L和A在说明书中详细定义。

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