where R is residue of uracil, thymine, cytosine or purine; R'' is hydrogen atom, acyl, alkyl, monophosphate, diphosphate or triphosphate or its pharmaceutically acceptable salts that show anti-HBV or anti- EBV activity. Invention describes also method of inhibition of HBV or EBV infection. EFFECT: new compounds indicated above, valuable antiviral properties. 13 cl, 20 dwg, 2 tbl, 5 ex"/> L-NUCLEOSIDES ELICITING ANTI-HBV OR ANTI-EBV ACTIVITY, METHOD OF INHIBITION OF HBV OR EBV INFECTION
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L-NUCLEOSIDES ELICITING ANTI-HBV OR ANTI-EBV ACTIVITY, METHOD OF INHIBITION OF HBV OR EBV INFECTION

机译:提倡抗-HBV或抗-EBV活性的L-核苷,抑制HBV或EBV感染的方法

摘要

FIELD: organic chemistry, biochemistry, virology. SUBSTANCE: invention describes novel L-nucleosides of the general formula (I) where R is residue of uracil, thymine, cytosine or purine; R'' is hydrogen atom, acyl, alkyl, monophosphate, diphosphate or triphosphate or its pharmaceutically acceptable salts that show anti-HBV or anti- EBV activity. Invention describes also method of inhibition of HBV or EBV infection. EFFECT: new compounds indicated above, valuable antiviral properties. 13 cl, 20 dwg, 2 tbl, 5 ex
机译:领域:有机化学,生物化学,病毒学。物质:本发明描述了通式(I)的新型L-核苷。<图像文件=“ 00000002.GIF” he =“ 37” id =“ imag00000002” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 33” / >其中R是尿嘧啶,胸腺嘧啶,胞嘧啶或嘌呤的残基; R”是氢原子,酰基,烷基,一磷酸,二磷酸或三磷酸或其显示出抗HBV或抗EBV活性的药学上可接受的盐。本发明还描述了抑制HBV或EBV感染的方法。效果:以上指出的新化合物,有价值的抗病毒特性。 13厘升,20载重吨,2汤匙,5前

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