Homo-conjugated triene preparation in high yield, by sequential Wittig reactions of bis-ylid with two aldehyde components, useful in synthesis of highly unsaturated fatty acids, leukotrienes or pheromones

摘要

The preparation of homo-conjugated trienes (I) involves: (a) reacting a bis-ylid (II) with a first aldehyde component (A1) under conditions such that only one ylid group of (II) reacts selectively; and (b) reacting the product with a second aldehyde component (A2).