Use of N,N',N'-tri(t-butoxycarbonyl)hydrazine-N-acetic acid or N,N'-di(t-butoxycarbonyl)hydrazine-N-acetic acid for functionalizing a peptide with a hydrazinoacetyl group

摘要

N,N',N'-Tri(t-butoxycarbonyl)hydrazine-N-acetic acid (I) or N,N'-di(t-butoxycarabonyl)hydrazine-N-acetic acid (II) is used for functionalizing a peptide with a hydrazinoacetyl group, either at the N terminus of the peptide or at the end of a lysine or ornithine side chain at any position in the peptide sequence.