Transgenic Alzheimer's disease animal model, useful for identifying compounds for treating neurodegeneration, contains several mutations in the presenelin 1 gene (PS1)

摘要

Transgenic animal (A) that expresses a multi-mutated form (I) of presenelin 1 (PS1) and can be used to detect apoptotic events in renewable peripheral tissues. An Independent claim is also included for cells derived from (A).