首页> 外国专利> Carrier protein having an adjuvant effect, immunogenic complex containing it, process for their preparation, nucleotide sequence and vaccine

Carrier protein having an adjuvant effect, immunogenic complex containing it, process for their preparation, nucleotide sequence and vaccine

机译:具有佐剂作用的载体蛋白,含有该蛋白的免疫原性复合物,其制备方法,核苷酸序列和疫苗

摘要

The invention relates to an adjuvant product which is intended to improve the activity of a molecule when administered to a host, characterized in that it comprises at least one part of the P40 protein of Klebsiella pneumoniae or a protein having at least 80% homology with the P40 protein of Klebsiella pneumoniae. The invention also relates to nucleotide sequences which encode these peptides or proteins and to the use of these sequences as a medicament. More particularly, such DNA sequences can be used in compositions which are intended for immunization by the intramuscular or intradermal route.
机译:本发明涉及一种佐剂产品,其旨在当施用于宿主时改善分子的活性,其特征在于它包含肺炎克雷伯氏菌(Klebsiella pneumoniae)的P40蛋白或具有与肺炎克雷伯氏菌的P40蛋白具有至少80%的同源性。本发明还涉及编码这些肽或蛋白质的核苷酸序列,并涉及这些序列作为药物的用途。更特别地,此类DNA序列可以用于旨在通过肌内或皮内途径进行免疫的组合物中。

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