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Polypeptides selectively reactive with antibodies against human immunodeficiency virus and vaccines comprising the polypeptides
Polypeptides selectively reactive with antibodies against human immunodeficiency virus and vaccines comprising the polypeptides
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机译:与抗人免疫缺陷病毒的抗体和包含该多肽的疫苗选择性反应的多肽
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摘要
Highly conserved polypeptide sequences derived from gp41 and gp120, preferably from eleven to twenty-one amino acids in length, are joined (for example, via DNA recombinant techniques) to a non-HIV protein or polypeptide sequence comprising an amino-acid sequence not naturally encoded by the HIV genome, thereby forming a fusion protein. Such fusion proteins possess attributes that make them suitable for use in the diagnosis, treatment and prevention of HIV infection.
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