N-(substituted 5- or diazatriunsaturated) carbonyl guanidine derivatives for the treatment of ischemia

摘要

This invention relates to NHE-1 inhibitors, methods of using such NHE-1 inhibitors and pharmaceutical compositions containing such NHE-1 inhibitors. The NHE-1 inhibitors are useful for the reduction of tissue damage resulting from tissue ischemia.