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Imidazopyrimidine nucleoside analogues with anti-HIV activity

机译:具有抗HIV活性的咪唑并嘧啶核苷类似物

摘要

The present invention accordingly provides imidazopyrimidine nucleoside compounds of formula (I) chemistry chemdraw filechemistry mol file;and a method for the treatment or prophylaxis of viral infections in mammals, including humans, comprising the step of administrating a therapeutically effective amount of said compound of formula (I), salts or esters of said compound, pharmaceutical acceptable derivatives or pharmaceutically acceptable salts or esters thereof. Further embodiments include the use of said nucleosides in the preparation of a medicament for the treatment of viral infections in mammals, a commercial packages and pharmaceutical formulations comprising said nucleosides as a therapeutically effective agents against an HIV infection.
机译:因此,本发明提供了式(I)的咪唑并嘧啶核苷化合物 <图像文件=“ US20020061896A1-20020523-C00001.GIF” he =“ 118.58805” id =“ EMI-C00001” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 191.5326“ /> 化学chemdraw文件 化学mol文件 ;以及用于治疗或预防包括人在内的哺乳动物的病毒感染的方法,包括给予治疗有效量的所述式(I)化合物的步骤,所述化合物的盐或酯,其药学上可接受的衍生物或药学上可接受的盐或酯。进一步的实施方案包括所述核苷在制备用于治疗哺乳动物中病毒感染的药物中的用途,包含所述核苷作为针对HIV感染的治疗有效剂的商业包装和药物制剂。

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