首页> 外国专利> Composition of boroprolina cyclic compounds, method for Manufacturing the pharmaceutical composition,Method for laproliferacion or stimulate the Activation of lymphocytes and human hematopoietic cells, and use of such compounds for preparing Medicine useful to stimulate Active

Composition of boroprolina cyclic compounds, method for Manufacturing the pharmaceutical composition,Method for laproliferacion or stimulate the Activation of lymphocytes and human hematopoietic cells, and use of such compounds for preparing Medicine useful to stimulate Active

机译:环丙脯氨酸环化合物的组合物,该药物组合物的制备方法,增殖或刺激淋巴细胞和人造血细胞活化的方法,以及此类化​​合物在制备可用于刺激活性成分的药物中的用途

摘要

Composition comprising a substantially Pure preparation of a compound of boroprolina cyclical has the structure of formula (i) wherein cadax1 and x2 is independentlyA hydroxyl group or a group can be hydrolyzed to a hydroxyl Group in aqueous solution at Physiological pH; and x represents an amino acid or Peptide mimics of a substrate Recognition siteA Post prolilo Enzyme decomposition.Method for the manufacture of pharmaceutical dichacomposicion methodof, stimulate the Activation and Proliferation of human hematopoietic cells or lymphocytes.And use of such compuestospara preparing Medicine useful to stimulate the Activation and Proliferation of human hematopoietic cells or lymphocytes
机译:包含基本上纯的硼环戊环化合物的制剂的组合物具有式(i)的结构,其中cadax1和x2独立地是羟基或一个基团可以在生理pH下在水溶液中水解成羟基; X代表底物识别位点的氨基酸或肽模拟物,脯氨酸酶分解。制造药物双歧化方法,刺激人造血细胞或淋巴细胞的活化和增殖的方法。人造血细胞或淋巴细胞的活化和增殖

著录项

  • 公开/公告号AR018440A1

    专利类型

  • 公开/公告日2001-11-14

    原文格式PDF

  • 申请/专利权人 POINT THERAPEUTICS INC.;

    申请/专利号AR1999P102605

  • 发明设计人

    申请日1999-06-02

  • 分类号C07F5/02;A61K31/69;A61P37/02;

  • 国家 AR

  • 入库时间 2022-08-22 00:46:33

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