Use of a cell made genetically comprising DNA encoding a Protein of Lymphocyte Activation Gene 3 (lag-3) and the transmembrane protein in the manufacture of a medicamentOr useful to induce Protection of graft rejection and the use of antisense Molecules of the same

摘要

The methods to prevent rejection of transplantation of cells, tissues or organs without general immunosuppression are described. Use the method rag -3, rediscover. When ectopic or heterotopic cells are used to express rag-3 on the surface and in the transplantation, the immune damage of the transplanted cells, tissues or organs can be prevented. In the host immune system, the particularity of this method makes it possible to prepare the gene therapy cells of the host. Universality, expression of rag-3 protein on the surface, as a protection of the host immune system for transplantation.