Compound, process for preparing the same, pharmaceutical composition, and methods for treating disease conditions mediated by matrix metalloproteinase in a mammal in need of it, and for treating a patient who is selected from the group that consists of osteoarthritis, rheumatoid arthritis, cartilage loss degenerative and tumor development

摘要

"COMPOUND, PROCESS TO PREPARE THE SAME, PHARMACEUTICAL COMPOSITION, AND METHODS FOR TREATING DISEASE CONDITIONS MEASURED BY THE MATRIX IN A MAMMALIAN WHO NEEDS THIS, AND TO TREAT A QUESTION OF QUESTION OF THESE CHARACTERISTIC DISEASE, DEGENERATIVE AND TUMOR DEVELOPMENT ". The compounds having formula (1) are useful in the treatment of disease conditions mediated by matrix metalloproteinases and TACE, such as tumor development, osteoarthritis, rheumatoid arthritis and cartilage loss.