Composition for inhibiting transcription activation, transcription repression, assembly of a bacterial holotoxin, actin polymerization, aggregation of a beta-amyloid peptide, assembly of a tubulin complex, inhibition method, method of treating and preventing human diseases such as Alzheimer's disease and cancer, a method for preparing a pharmaceutical and the pharmaceutical per se

摘要

The present invention is related to the discovery of peptides that modulate the protein-protein interactions necessary for protein polymerization and the assembly of supramolecular protein complexes. More specifically, biotechnological tools and medicaments comprising various small peptides that have a modified carboxyl terminus are disclosed for use in the study and treatment or prevention of human disease.