METHOD OF SUBSTANTIALLY CONTINUOUSLY SEPARATING TWO COMPOUNDS USING A MOVING BED OR A SIMULATED MOVING BED

摘要

The present invention relates to a method of separating a first solute A and a second solute B using (simulated) moving bed chromatography. According to the present invention at least one of a) a feedstream; and b) a desorbent stream comprises an organic solvent. The use of different solvent liquids for the feedstream and the desorbent stream results in an increased difference in partition coefficients for solute A and solute B. According to the present invention it is possible to obtain solute A in an extract stream in a form which is more concentrated in comparison to the concentration of solute A in the feedstream.