首页> 外国专利> The compound, processes for preparing the compound to a specific recognition by following a polinucleotu00eddio double filament, to modulate the expression of a gene in an organism.To treat conditions associated with unwanted protein production in a body.To induce the degradation of DNA or RNA in cells of an organism and to exterminate cells or viruses, and the pharmaceutical composition

The compound, processes for preparing the compound to a specific recognition by following a polinucleotu00eddio double filament, to modulate the expression of a gene in an organism.To treat conditions associated with unwanted protein production in a body.To induce the degradation of DNA or RNA in cells of an organism and to exterminate cells or viruses, and the pharmaceutical composition

机译:该化合物的制备方法是通过遵循多聚核苷酸双细丝来调节化合物的特异性表达,从而调节生物体中基因的表达。治疗与体内有害蛋白质产生相关的疾病。诱导DNA降解生物体细胞中的RNA或RNA,并消灭细胞或病毒,以及药物组合物

摘要

A novel class of compounds, known as peptide nucleic acids, bind complementary ssDNA and RNA strands more strongly than a corresponding DNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases attached to a peptide backbone through a suitable linker.
机译:一类新的化合物,称为肽核酸,比相应的DNA更牢固地结合互补ssDNA和RNA链。肽核酸通常包含配体,例如通过合适的接头连接至肽主链的天然存在的DNA碱基。

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