NOVEL POLYPEPTIDE--- A HUMAN PEROXISOME FATTY ACID ACETYL COA OXIDASE 14.85 AND POLYNUCLEOTIDE ENCODING IT

摘要

The invention concerns a human peroxisome fatty acid acetyl CoA oxidase 14.85 and polynucleotide encoding it. The invention also concerns the process of producing the polypeptide by recombinant DNA technique. The methods for treating many diseases e.g. human peroxisome fatty acetyl CoA oxidase deficiency syndrome, fatty acid metabolic disturbance diseases, fatty degeneration disease, cardiovascular disease, related tumors, immunological diseases and a variety of inflammation etc. utilizing the polypeptide are disclosed. The invention discloses the antagonist against the polypeptide and therapeutics thereof. The invention also discloses the uses of the polynucleotide, which encodes a human peroxisome fatty acetyl CoA oxidase 14.85.