首页> 外国专利> 47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, AND 84234, NOVEL HUMAN GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR, GLYCOSYLTRANSFERASE, DEAD TYPE HELICASE, CENTAURIN, DEHYDROGENASE/REDUCTASE, AND METAL TRANSPORTER FAMILY MEMBERS AND USES THEREOF

47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, AND 84234, NOVEL HUMAN GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR, GLYCOSYLTRANSFERASE, DEAD TYPE HELICASE, CENTAURIN, DEHYDROGENASE/REDUCTASE, AND METAL TRANSPORTER FAMILY MEMBERS AND USES THEREOF

机译:47476,67210,49875,46842,33201,83378,84233,64708,85041和84234,新型人类鸟嘌呤核苷酸解离刺激物,糖基转移酶,死型解旋酶,CENTAURIN,脱氢酶/还原酶,以及金属转运蛋白和金属蛋白酶

摘要

The invention provides isolated nucleic acids molecules, designated 47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, and 84234 nucleic acid molecules, which encode novel Guanine Nucleotide Dissociation Stimulator, Glycosyltransferase, DEAD type helicase, Centaurin, Dehydrogenase/Reductase, and Metal Transporter family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, or 84234 nucleic acid molecules, host cells nt which the expression vectors have been introduced, and nonhuman transgenic animals in which a 474476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, or 84234 gene has been introduced or disrupted. The invention still further provides isolated 47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, or 84234 proteins, fusion proteins, antigenic peptides and anti-47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, or 84234 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
机译:本发明提供了分离的核酸分子,其命名为47476、67210、49875、46842、33201、83378、84233、64708、85041和84234核酸分子,其编码新型鸟嘌呤核苷酸解离刺激剂,糖基转移酶,DEAD型解旋酶,人尿素,脱氢酶/还原酶和金属转运蛋白家族成员。本发明还提供了反义核酸分子,含有47476、67210、49875、46842、33201、83378、84233、64708、85041或84234核酸分子的重组表达载体,已经引入表达载体的宿主细胞和非人类导入或破坏了474476、67210、49875、46842、33201、83378、84233、64708、85041或84234基因的转基因动物。本发明还进一步提供了分离的47476、67210、49875、46842、33201、83378、84233、64708、85041或84234蛋白,融合蛋白,抗原肽和抗47476、67210、49875、46842、33201、83378、84233, 64708、85041或84234抗体。还提供了利用本发明的组合物的诊断方法。

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