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METHOD OF KILLING TARGET CELLS IN HARVESTED CELL POPULATIONS WITH TWO IMMUNOTOXINS

机译:用两种免疫毒素杀死被收获细胞群体中的靶细胞的方法

摘要

A method for killing unwanted target cells in a cell population comprising nucleated cells harvested from peripheral blood, or CD-34+ or similar early progenitor cells selected from the above nucleated cells or from bone marrow aspirates, in which method the cell population is in vitro or in vivo exposed to two or more immunotoxins selectively killing the malignant cells, is described. Furthermore the invention relates to the mixture of immunotixins, the use of the mixture and a kit for performing the method.
机译:一种用于杀死细胞群中不需要的靶细胞的方法,所述细胞群包括从外周血中收获的有核细胞,或选自上述有核细胞或骨髓穿刺细胞的CD-34 +或类似的早期祖细胞,其中该细胞群是体外的描述了在体内或体内暴露于两种或多种选择性杀死恶性细胞的免疫毒素的方法。此外,本发明涉及免疫毒素的混合物,该混合物的用途和用于进行该方法的试剂盒。

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