METHOD OF REGULATORY ACTION ON PRIMARY MECHANISMS OF BODY DEFENSE REACTIONS IN NORMAL AND PATHOLOGICAL STATES: IMMUNE REACTION, INFLAMMATORY REACTIONS, AND FREE-RADICAL PROCESS USING GAMMA-GLUTAMYLHISTAMINE

摘要

FIELD: pharmacology. SUBSTANCE: invention relates to treatment of diseases, whose pathogenesis mechanisms have, as primary biochemical steps, release of histamine from its depot and/or hyperactivation of free-radical process. Invention proposes use of gamma- glutamylhistamine in doses from 0.01 to 250 mg per 1 kg body weight. Preparation is nontoxic and is characterized by considerable spectrum of therapeutic action. EFFECT: enabled combination of immunocorrecting, antiallergic, wound- healing, anti-inflammatory, and antioxidant effects. 5 cl, 15 dwg, 7 tbl