Cross-flow filter cassette used in the pharmaceutical and biotechnology industries has an overflow gap formed from a retentate distance spacer element and retentate distance spacer frames

摘要

Cross-flow filter cassette has an overflow gap (4) formed from a retentate distance spacer element (3) and two retentate distance spacer frames (3', 3'') which cover the element on both sides of its flat edge regions. The spacer element is made from an open mesh matrix built up from crossing longitudinal and cross fibers. Neighboring fibers are spaced by 5 to 15 times their thickness lying in the region of 150-600 mu m. The frames have a thickness of 50-200 mu m. Preferred Features: The longitudinal and cross fibers are connected at their crossing points and consists of organic polymer fibers fused to the crossing points by extrusion. The fibers lie in one plane in the matrix. The cassette also has microporous membranes (5) made from hydrophilic microfiltration membranes of crosslinked cellulose hydrate.