Devising optimal strategy for diagnosis of microtissue arrays, useful e.g. for detecting tumor-related genomic abnormalities, by computer modeling of cell nuclei

摘要

Method for calculating the optimal strategy for molecular multiplex diagnosis of microtissue arrays involves calculating a computer model of the nuclei of the cell type(s) being examined. The model describes suitable light-optical, detectable properties of the sites that are to be labeled, e.g. specific spectral signatures or combinations of them.