APOPTOSIS INDUCER, COMPOUND HAVING APOPTOSIS INDUCING ACTIVITY, ANTICANCER AGENT, DRUG SCREENING METHOD AND DRUG SCREENING KIT

摘要

PPROBLEM TO BE SOLVED: To obtain an apoptosis inducer suitably usable as an anticancer agent or in screening anticancer agents, or the like, to provide such an anticancer agent highly effective in cancer therapy, to provide a drug screening method capable of efficiently selecting new drugs including such anticancer agents, or the like. PSOLUTION: A polypeptide consisting of an amino acid sequence as a part or the whole containing at least cyclin box of cyclin G2 is provided. The apoptosis inducer comprising a polypeptide which consists of one of amino acid sequences where one or more amino acids is (are) deleted from, substituted for or added to the above amino acid sequence and has apoptosis-inducing activity is also provided. PCOPYRIGHT: (C)2003,JPO