首页>
外国专利>
ARV1, a protein involved in sterol uptake and sterol hemeostasis in the budding yeast, S. cerevisiae, and a functional human ARV1
ARV1, a protein involved in sterol uptake and sterol hemeostasis in the budding yeast, S. cerevisiae, and a functional human ARV1
展开▼
机译:ARV1,一种与芽生酵母,酿酒酵母和功能正常的人ARV1相关的固醇摄取和固醇血肿的蛋白质
展开▼
页面导航
摘要
著录项
相似文献
摘要
This invention provides an isolated nucleic acid which encodes mammalian ACAT-Related Enzyme 2 Required for Viability protein (ARV1p), wherein the encoded ARV1p protein has the amino acid sequence set forth in FIG. 7. This invention provides an isolated nucleic acid which encodes yeast ACAT-Related Enzyme 2 Required for Viability protein (ARV1), wherein the encoded ARV1 protein has the amino acid sequence set forth in FIG. 5. This invention provides a purified mammalian ACAT-Related Enzyme 2 Required for Vialbility protein (ARV1p) having the amino acid sequence set forth in FIG. 7. This invention provides a purified yeast ACAT-Related Enzyme 2 Required for Vialbility protein (ARV1p) having the amino acid sequence set forth in FIG. 5. This invention provides a method for identifying a chemical compound which is capable of inhibiting or stimulating ACAT-Related Enzyme 2 Required for Viability protein (ARV1p) which is capable of inhibiting ARV1p. Methods of treatment using pharmaceutical compositions of the invention asre also provided.
展开▼