Lactate thiolester for cardiac energy resuscitation and prevention of reperfusion injury and use as an energy supplement during exercise and recovery

摘要

The invention comprises a novel lactate compound for two unique purposes: (1) cardiac energy resuscitation and the treatment or prevention of reperfusion injury following ischemia, and (2) the provision of a fuel energy source to humans and other mammals during exercise and recovery. The novel lactate compound is particularly a lactate thiolester. Preferably, the thiol is selected from a cysteine or a methionine amino acid. In a particularly preferred form, the compound is a lactate N-acetyl ethyl ester of the cysteine or methionine amino acid. The most preferred compound is lactate N-acetyl cysteine thiolester (LNACE): ;Further, the invention involves use of mixtures of lactate- and pyruvate compounds as well as hexoses (glucose and fructose), maltodextrins and electrolytes as adjutants to support LNACE in its specific purposes.