;wherein: m and n are independently 0, 1, 2 or 3, X is a group that is negatively or positively charged at physiological pH, R, R1, R2 and R3 are independently hydrogen, C1-C4 alkyl, or a carboxyl group, and I* is 123I, 131I or 125I, and its pharmaceutically-acceptable salts. The compound is formulated and used in vivo in an animal in brachytherapy in an implantable catheter. In addition, due to the rapid renal clearance of these compounds, they may be used to study renal function. A process to prepare these compounds is also disclosed."/>
公开/公告号US6506364B1
专利类型
公开/公告日2003-01-14
原文格式PDF
申请/专利权人 THE DOW CHEMICAL COMPANY;
申请/专利号US20000672541
申请日2000-09-28
分类号A61K510/00;G01N230/00;
国家 US
入库时间 2022-08-22 00:06:24