Pteridine analysis by capillary electrophoresis using laser-induced fluorescence detection

摘要

The present invention provides a unique method and means for detecting pteridines in biological samples using the novel combination of capillary electrophoresis (CE) and laser-induced fluorescence detection (LIF). The method is effective in detecting eight pteridine compounds at very low detection limits of less than about 1×10^−10 M. The method allows for the detection of pteridines for various purposes involving metabolism and function investigation, including cancer monitoring and precancer screening.